3
Orphan Designations
0
FDA Approvals
8
Rare Diseases
0
News Articles
| Disease | Drug(s) | Designation | Approved |
|---|---|---|---|
| Kabuki syndrome 1 | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| Smith-Lemli-Opitz syndrome | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| gastric cancer | fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin 18.2). | Orphan Designation | - |
| gastric leiomyosarcoma | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| gastric lymphoma | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| gastric ulcer | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| gastric volvulus, intrathoracic | humanized IgG4 monoclonal antibody optimized for neutralizing activity against DKK1, a secreted modulator of Wnt signaling | Orphan Designation | - |
| malignant pancreatic neoplasm | Anti-Claudin 18.2 Antibody consisting of a fully human monoclonal IgG1 antibody to the type 2 isoform of human Claudin 18 protein | Orphan Designation | - |