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REST API

Rare disease data. One API call.

15,964 diseases with clinical phenotypes, genetic associations, orphan drugs, news intelligence, and patient resources. Start free. Scale when ready.

1,000 API calls/month free. No credit card required.

15K+
Rare diseases
with structured data
31+
Phenotypes
per disease (HPO)
8.3K+
Gene links
NCBI-validated
7618+
Orphan drugs
FDA designations
56
Screening
RUSP conditions
1.3K+
Patient groups
verified PAGs

Try it now — no signup needed

Search any disease and see a real API response.

Try the API

Search any disease and see the full API response. No signup required.

Try:

Everything you need per disease

Structured clinical data, not just summaries.

Clinical Phenotypes

HPO-mapped symptoms with frequency tiers

Gene Associations

NCBI-linked genes with inheritance patterns

Orphan Drug Data

FDA designations with approval status

Screening Status

RUSP newborn screening coverage

Patient Organizations

Verified PAGs with contact information

Cross-References

OMIM, Orphanet, GARD, ICD codes

7 Content Sections

Overview, symptoms, diagnosis, treatment, etc.

Prevalence Data

Orphanet epidemiological estimates

News Intelligence

AI-classified disease news with entity extraction

Start free. Scale when ready.

No credit card required. Upgrade as your usage grows.

Free

$0forever

For developers exploring rare disease data

  • 1,000 API calls/month
  • All disease data endpoints
  • Disease search & typeahead
  • News intelligence feed
  • Community support
Start Free
Most Popular

API Self-Serve

$500/month

For teams building healthcare products

  • 50,000 API calls/month
  • Everything in Free, plus:
  • Full REST API (18+ endpoints)
  • Webhook support
  • Policy data endpoints
  • Standard support (48hr)
Get API Access

Enterprise

Custom

For pharma, biotech & large organizations

  • Unlimited API calls
  • Everything in Self-Serve, plus:
  • Competitive intelligence
  • Cross-disease analytics
  • SSO/SAML + SLA guarantee
  • Dedicated account manager
Talk to Sales

Five lines of code to your first API call

JavaScript / TypeScript
// JavaScript / TypeScript
const response = await fetch(
  'https://api.kishomed.io/v1/diseases/MONDO:0007915',
  {
    headers: {
      'Authorization': 'Bearer kisho_live_xxxxx...'
    }
  }
);

const disease = await response.json();
console.log(disease.name); // "Duchenne muscular dystrophy"
console.log(disease.sections.overview);
console.log(disease.phenotypes);

What teams build with KISHO

See real-world applications powered by the API

For Medical Affairs

Rare Disease News Intelligence

AI-classified news from 25+ sources with executive summaries, disease auto-tagging, and entity extraction

Replace $100K/year monitoring services
Try Demo
For Digital Health Teams

AI Disease Assistant

Embed a conversational AI into patient portals. Disease Q&A, news, patient assistance, and PAG discovery via natural language.

One API call, no medical writers needed
Try Demo
For Life Sciences

CI Briefs

Generate executive-ready competitive landscape briefs for medical affairs teams

4 API calls in 3 seconds
Try Demo
For Digital Health

Disease Content Widget

Embed comprehensive disease information directly into patient portals and care apps

Ship in days, not months
Try Demo
For Clinical Genomics

Gene-to-Disease Lookup

Map genetic variants to rare diseases for variant interpretation workflows

Map variants instantly
Try Demo

Built for regulated environments

Every data point is sourced, versioned, and audit-ready.

HIPAA Compliant

No PHI stored. Content-only API designed for healthcare.

Full Audit Trail

Version history and contributor tracking for compliance.

Quality Controlled

HGNC gene validation, fact-checking, and automated review.

99.9% SLA

Enterprise plans include uptime guarantee.

Service Level Agreement

Enterprise tier commitments

Uptime

99.9% monthly availability target

Response Time

p95 < 500ms for disease data endpoints

Support

24hr response (business days), dedicated account manager for Enterprise

Rate Limits

10K/mo (Free), 50K/mo (Self-Serve), Unlimited (Enterprise)

Grounded in the same sources researchers and hospitals trust

MONDO

Disease Ontology

23,529 diseases

HPO

Phenotype Ontology

18,000+ phenotypes

FDA

Drug Data

Orphan drugs + approved

ClinicalTrials.gov

Trial Registry

Active trial counts

Orphanet

Epidemiology

6,028 prevalence records

OMIM

Genetic Database

Gene-disease links

PubMed

Literature

Citation enrichment

HGNC

Gene Nomenclature

44,748 gene symbols

GARD

NIH Information

Cross-references

RUSP

Newborn Screening

Screening status

Already paying for disease content?

See how Kisho compares to medical writers, agencies, and in-house builds.

15,964+ Rare Diseases

Ready to integrate today

Deploy in Days

Not months or years

QC-Validated

HGNC gene validation, fact-checking, safety checks

Calculate Your Savings

See how Kisho compares to building in-house or hiring content teams.

100
101,0005,000+
Save $183K (96%)

With Kisho Starter at $8K/year, compared to the next cheapest option.

ApproachYear 1 CostRisk
Hire Medical Writer$247K
High
Commission Agency$350K
Medium
Build In-House$190K
High
Kisho Starter$8K/yr
Low

Need content this week?

Only Kisho can deliver 15,964+ rare disease records immediately. Other options require months of development.

Start building in the next 5 minutes

Create a free account, get your API key, and make your first call. No credit card. No sales call.

Questions?

Talk to our team about your use case, volume requirements, or custom integrations.

Contact Us