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Kisho - Rare Intelligence
Developer/Changelog

API Changelog

Version history and changes for the Kisho Disease Content API

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Current Version

v1.2.0

Computed intelligence fields and enhanced search filters

2026-01-06

v1.2.0

minor2026-01-06

Computed intelligence fields and enhanced search filters

added
  • •New `computed` object in disease responses with 20+ derived fields
  • •New `classification` object with quick signals (unmetNeedSignal, pipelineActivity, researchActivity)
  • •New search filters: hasActiveTrials, minTrialCount, hasExpertContent, inheritancePattern, onsetCategory, prevalence, gene
  • •New sort options: label, activeTrialCount, updatedAt, pagCount
  • •New endpoint: `GET /api/v1/diseases/bulk` for fetching up to 50 diseases at once
  • •Pagination support with offset parameter in search endpoint
  • •Highlighting support with `highlight=true` parameter
  • •Facet counts with `facets=true` parameter
changed
  • •Search results now include additional fields: hasActiveTrials, activeTrialCount, inheritancePatterns, onsetCategories, prevalenceCategory
  • •Improved search response with pagination object (limit, offset, hasMore)
  • •Updated OpenAPI spec to v1.2.0 with full schema documentation

v1.1.0

minor2025-12-15

Phenotype and orphan drug endpoints

added
  • •New endpoint: `GET /api/v1/diseases/{mondoId}/phenotypes` - HPO phenotype data
  • •New endpoint: `GET /api/v1/diseases/{mondoId}/orphan-drugs` - FDA orphan designations
  • •New endpoint: `GET /api/v1/diseases/{mondoId}/screening` - Newborn screening status
  • •Added `qualityScore` field to disease metadata
changed
  • •Increased default rate limit for Professional tier to 10,000/day
  • •Improved search relevance scoring

v1.0.0

major2025-11-01

Initial public release

added
  • •Core disease endpoints: list, search, get by MONDO ID
  • •Disease sections endpoint for individual content sections
  • •Disease summary endpoint for lightweight responses
  • •PAG (Patient Advocacy Group) endpoint
  • •Patient assistance programs endpoint
  • •API key authentication with Bearer tokens
  • •Rate limiting with tier-based quotas (Developer, Professional, Enterprise)
  • •OpenAPI 3.0 specification at /api/v1/openapi
  • •Health check endpoint at /api/v1/health
  • •ETag caching support with If-None-Match headers

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