acute monocytic leukemia

Acute monocytic leukemia (also known as acute monoblastic leukemia or AML-M5) is a subtype of acute myeloid leukemia. It is characterized by a high number of abnormal white blood cells, which are either mostly monoblasts (AML-M5a) or a mix of monoblasts and (pro)monocytes (AML-M5b). People with this condition may experience a variety of symptoms and laboratory findings. This disease is noted for specific features including very high white blood cell counts, signs of leukemia cutis, and infiltration of the gums, along with other systemic effects that are part of its clinical presentation.

People with acute monocytic leukemia often experience weakness, pallor (pale skin), fever, and dizziness. They may also have other signs due to high white blood cell counts, such as bleeding or clotting problems, neurological issues, and skin or gum involvement. These symptoms are linked to the ways the abnormal cells affect different parts of the body.

In acute monocytic leukemia, a characteristic genetic change, the translocation t(9;11), is often observed. This abnormality plays a role in the development of the condition. There is no further detailed genetic or environmental cause information provided in the source.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research on this condition is currently limited.