Thiemann disease, familial form

Thiemann disease, familial form is a very rare genetic bone disorder that affects the ends of the bones in the fingers. People with this condition often experience painless swelling in the middle joints of the fingers. Over time, the affected bone areas can undergo changes that resemble early arthritis. This disorder typically begins before the age of 25 and is described as having a benign course in many cases, meaning that while there are changes in the bones, the progression may not be severe. The condition is also known by several other names, including osteochondrosis of phalangeal epiphyses and Thiemann's disease.

People with Thiemann disease may notice painless swelling in the proximal interphalangeal joints, which are the middle joints of the fingers. Over time, these joints can show signs of osteonecrosis and osteoarthritis.

Thiemann disease is described as a genetic disorder. It appears to run in families, indicating that genetic factors play a role in the condition. However, no specific gene has been identified as a cause.

Information about treatment is currently limited for this condition.

Many people with Thiemann disease experience a benign course, meaning that the condition may not progress severely. However, changes in the bones, such as osteoarthritic features, can occur over time.

Information about current research and future directions is currently limited for this condition.