Dandy-Walker syndrome

Dandy-Walker syndrome is a rare brain malformation that affects the cerebellum, a part of the brain important for balance and coordination, as well as the surrounding fluid spaces. It is marked by three main features: hydrocephalus (an excess buildup of fluid in the brain), a partial or complete absence of the cerebellar vermis, and a cyst in the posterior fossa that is continuous with the fourth ventricle. This condition is typically noticed early in life, with signs such as a bulging occiput (back of the head) in infants and various neurological symptoms. People with this condition may experience issues that affect balance and movement, as well as eye movements and some nerve functions.

Common symptoms of Dandy-Walker syndrome include hydrocephalus, a bulging occiput, cranial nerve palsies, nystagmus (rapid, involuntary eye movements), and ataxia (difficulty with balance and coordination).

The exact causes of Dandy-Walker syndrome are not fully understood. There is some evidence of a genetic link, as indicated by the known gene marker 'DWS', but further research is needed to fully explain the role of genetics and any additional risk factors.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.