Alzheimer disease without neurofibrillary tangles

Alzheimer disease without neurofibrillary tangles, also known as AD15 or Alzheimer's disease type 15, is a rare variant noted in genetic databases. Unlike the more commonly known form of Alzheimer disease, this variant is characterized by the absence of neurofibrillary tangles, a feature often seen in typical cases. This difference has led researchers to consider this condition as a distinct form of neurodegenerative disease. Limited available data suggests that genetic factors may play a role in this condition. For example, the AD15 gene has been identified as being associated with this type. The condition is registered in genetic resources such as OMIM and the Genetic and Rare Diseases (GARD) database, reflecting ongoing efforts to better understand its characteristics and implications.

Information about symptoms is currently limited for this condition.

The genetic component, particularly the involvement of the AD15 gene, is noted in connection with this condition. However, details about additional causes or risk factors are sparse and more research is needed to clarify these aspects.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Current research on Alzheimer disease without neurofibrillary tangles includes genetic studies and clinical observations. Resources like OMIM and GARD provide foundational information, although more detailed studies are needed to better understand its underlying mechanisms and to explore potential therapies.