Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease is an inherited condition that affects the peripheral nerves. These nerves carry signals between the brain and the rest of the body and control movement and sensation. This condition is caused by mutations in genes that make proteins important for the structure and function of peripheral nerves. Over time, people with this condition may experience muscle weakening and shrinking (atrophy), especially in the feet, legs, hands, and arms, along with a loss of sensation in these areas.

People with Charcot-Marie-Tooth disease may experience muscle weakness and atrophy in their limbs. They might notice loss of sensation, particularly in the feet and hands, which can affect balance and coordination.

Charcot-Marie-Tooth disease is caused by genetic mutations that affect the proteins necessary for the proper function and structure of peripheral nerves. This inherited mutation leads to the gradual degeneration of these nerves, causing the symptoms observed in the condition.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.