adenocarcinoma of gallbladder and extrahepatic biliary tract

Adenocarcinoma of the gallbladder and extrahepatic biliary tract is a rare type of cancer that starts in the gland cells lining the gallbladder or the bile ducts outside the liver. This cancer is part of a group called epithelial carcinomas and can sometimes present with symptoms that make it look like less serious biliary diseases. Because the disease arises from the cells in the gallbladder or the extrahepatic biliary tree, its early signs can be vague. In many instances, the symptoms are nonspecific, making diagnosis challenging. This overview provides a basic understanding of the condition based on the currently available definitions.

People with this condition may experience abdominal pain, jaundice (yellowing of the skin or eyes), and vomiting. These symptoms are often nonspecific and can be similar to those seen in non-cancerous biliary diseases.

The exact causes of adenocarcinoma of the gallbladder and extrahepatic biliary tract are not fully understood. However, chronic inflammation of the biliary epithelium is considered a major risk factor. Conditions that may lead to chronic inflammation include primary sclerosing cholangitis, gallstones (cholelithiasis), bile duct stones (choledocholithiasis), and liver fluke infestation.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.