CREST syndrome

CREST syndrome is a subtype of limited cutaneous systemic sclerosis. The name CREST is an acronym that stands for calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. This condition involves changes in the skin and internal organs, and it has distinct clinical features that help doctors recognize it. People with CREST syndrome experience a range of symptoms related to these five key features. The condition is one form of systemic sclerosis and is generally different from other types of scleroderma, which can involve more widespread skin changes and different internal complications.

Common features of CREST syndrome include calcinosis (calcium deposits under the skin), Raynaud's phenomenon (changes in blood flow to the fingers and toes, leading to color changes and discomfort), esophageal dysmotility (difficulty with the movement of the esophagus), sclerodactyly (thickening and tightening of the skin on the fingers), and telangiectasia (small dilated blood vessels on the skin). These symptoms form the basis of the CREST syndrome name.

Information about causes, genetics, and risk factors is currently limited for this condition.

Information about treatment options and management approaches is currently limited for this condition.

Information about the outlook and quality of life for people with this condition is currently limited.

Information about current research and future directions is currently limited for this condition.