focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis is a kidney disorder that involves scarring (sclerosis) in parts of some of the filtering units in the kidney called glomeruli. This scarring can affect the kidney's ability to filter waste from the blood. The condition can be caused by factors such as certain drugs, viral infections, or malignancies like lymphomas, but in some cases, the cause is unknown (idiopathic). It may present without symptoms aside from protein in the urine (proteinuria) or with signs of nephritic syndrome, and over time, the damage can lead to renal failure.

People with this condition may show signs such as the presence of protein in the urine without other symptoms (asymptomatic proteinuria) or symptoms associated with nephritic syndrome. These signs point to a disruption in normal kidney function.

This kidney disorder can be triggered by several factors. It may occur as a result of exposure to certain drugs, viral infections, or malignancies such as lymphomas. In other cases, the condition arises without a clear cause (idiopathic).

Information about treatment is currently limited for this condition.

In focal segmental glomerulosclerosis, the kidney scarring can potentially lead to renal failure over time. The long-term outlook and quality of life for people with this condition can vary, and more detailed information is currently limited.

Information about current research and future directions is currently limited for this condition.