gingival fibromatosis-progressive deafness syndrome

Gingival fibromatosis-progressive deafness syndrome is a condition where people experience an overgrowth of the gums (gingival fibromatosis) along with a gradual loss of hearing (progressive sensorineural hearing loss). It has been observed in two families, with several affected members across multiple generations. This suggests that the condition is passed down in families in an autosomal dominant pattern. The syndrome has been described in detail in these family studies. People with this condition may show symptoms that develop over time with gum changes and a decline in hearing. Although the syndrome is rare, the available family histories underline the importance of genetic factors in its development.

The main symptoms include thickened, overgrown gums (gingival fibromatosis) and a loss of hearing that gets worse over time (progressive sensorineural hearing loss).

This condition appears to be caused by genetic factors. It is passed down through families in an autosomal dominant manner, which means that a single copy of the altered gene in each cell is enough to cause the disorder. No specific genes or environmental risk factors have been identified beyond this pattern.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.