Morvan syndrome

Morvan syndrome is a rare and life-threatening acquired neurological disease. It is marked by a mix of symptoms affecting the central nervous system, such as hallucinations, confusion, memory loss, and myoclonus (sudden muscle jerks). Along with these, there is dysautonomia, which involves problems with the body's automatic functions like blood pressure regulation and sweating. Severe insomnia is also a key feature of this condition. In addition to the central nervous system issues, people with Morvan syndrome may experience peripheral symptoms like painful cramps and continuous muscle twitching (myokymia), as well as systemic complaints including weight loss, fever, and itching. In some cases, a thymoma (a tumor in the thymus gland) is found, which may be related to the development of the syndrome.

Common symptoms in people with Morvan syndrome include signs from the central nervous system such as hallucinations, confusion, memory difficulties, and muscle jerks. Autonomic symptoms may include variations in blood pressure and excessive sweating. Other symptoms can involve peripheral nerve issues like painful muscle cramps and myokymia, along with systemic signs like weight loss, fever, and itching.

Morvan syndrome is an acquired condition, meaning it is not inherited. It has been linked in some cases to a thymoma, a tumor of the thymus gland. There are no identified genetic causes for this condition, and its exact trigger remains not fully understood.

Information about treatment is currently limited for this condition.

Morvan syndrome is considered life-threatening due to the severity and range of its symptoms. While the outlook can vary from person to person, detailed information about long-term outcomes and quality of life is currently limited.

Information about research is currently limited for this condition.