Fuchs heterochromic iridocyclitis

Fuchs heterochromic iridocyclitis (FHI) is a rare eye condition that affects a small number of uveitis cases. It is known for causing differences in iris color (heterochromia) or thinning (atrophy) of the iris. The condition also includes the appearance of small, dispersed inflammatory cells called keratic precipitates on the inner surface of the cornea. These features are seen without the usual adhesions (synechiae) that often occur in other inflammatory eye diseases. In some cases, FHI can lead to additional eye problems, such as increased eye pressure (glaucoma) or cloudiness in the vitreous, the gel that fills the inside of the eye. Because the cause of the condition is unknown and it affects only a small percentage of uveitis cases (0.5-6.2%), more research is needed to understand this disease fully. People with this condition may experience a slow progression, and symptoms can vary from person to person.

People with Fuchs heterochromic iridocyclitis can show a range of symptoms. Common signs include a change in iris color or tissue thinning and the presence of keratic precipitates on the cornea. While many people do not have the typical symptoms of eye inflammation, some may eventually develop complications such as increased eye pressure (glaucoma) or vitreous opacities, which can cause blurry or diminished vision.

The exact cause of Fuchs heterochromic iridocyclitis is not known. There is no clear evidence linking the condition to genetic factors or specific risk factors. Researchers have not yet determined why it occurs in some people, and the underlying reasons remain unclear.

Information about treatment is currently limited for this condition.

The outlook for people with Fuchs heterochromic iridocyclitis varies. In many cases, the condition remains stable over time, but some individuals may experience complications such as glaucoma or vitreous opacities, which can affect vision. Detailed long-term outcome information is limited, and quality of life considerations depend on individual circumstances and the management of any complications.

Information about research is currently limited for this condition.