Bartter syndrome type 4

Bartter syndrome type 4 is a rare condition that affects the kidneys and is also linked to hearing loss. This condition is marked by problems such as loss of salt in the body, extra urination (polyuria), and metabolic changes. It is noted for an imbalance in key electrolytes, with lower levels of potassium and chloride, and changes in how the body handles certain hormones that help regulate blood pressure and kidney function. The condition is also associated with complications during pregnancy, such as high levels of amniotic fluid (polyhydramnios) and premature delivery. Although the levels of urinary calcium can vary, the typical kidney damage seen in similar disorders, called nephrocalcinosis, is generally absent. This summary is based on the current available information from trusted sources.

People with Bartter syndrome type 4 may show symptoms that include signs of salt loss, increased urination, and sensorineural deafness (hearing loss). There are also metabolic changes such as low blood levels of potassium and chloride, and changes in hormones like renin and aldosterone, even though blood pressure tends to be low to normal.

Information about causes is currently limited for this condition.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.