RhizoKids International supports individuals with Rhizomelic Chondrodysplasia Punctata (RCDP) through research programs, awareness events, and conferences aimed at improving the quality of life for affected families.

Riaan Research Initiative is dedicated to accelerating the development of treatments for Cockayne syndrome, a severe genetic disorder, by promoting and funding innovative research proposals.

Riverwood Center provides compassionate behavioral health, substance use disorder, and wellness services to individuals and families in Berrien County, Michigan, supporting mental health and overall well-being.

Ronald McDonald House provides support and resources for families with children who are ill or injured, offering them a place to stay close to hospitals and ensuring they have the comforts of home during difficult times.

The Rothmund-Thomson Syndrome Foundation raises awareness and supports research for Rothmund-Thomson Syndrome, a rare genetic disorder, while providing resources and community for affected individuals and families.

SADS UK is the UK's leading cardiac charity focused on raising awareness and providing support for Sudden Arrhythmic Death Syndrome and related inherited cardiac conditions.

SANE Australia provides support for individuals with complex mental health issues and trauma, offering free digital and telehealth services, community forums, and resources for recovery.

The SATB2 Gene Foundation, Inc. supports families of individuals with SATB2-associated syndrome through awareness, research, and education.

SETBP1 Society supports families impacted by SETBP1 haploinsufficiency disorder (SETBP1-HD) and related disorders, focusing on advancing research for effective treatments and improved quality of life.

SHARE Cancer Support is a national nonprofit organization that provides support and education for individuals diagnosed with breast and gynecologic cancers, offering various services including helplines, support groups, and educational webinars.

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Snap25 Foundation is dedicated to advocating for children affected by Snap25 disorders, which often lead to severe epilepsy and intellectual disabilities, by promoting research, awareness, and community support.

The SSADH Association is dedicated to supporting children and families affected by Succinic Semialdehyde Dehydrogenase Deficiency (SSADH), an ultra-rare neurometabolic disorder, through education, advocacy, and research.

The STAG1 Gene Foundation is a patient-led organization that supports individuals with the STAG1 gene mutation by providing knowledge, resources, and advocacy to families and clinicians.

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The STXBP1 Foundation is dedicated to raising awareness and finding a cure for STXBP1-Related Disorder, a rare neurodevelopmental condition and genetic epilepsy, by working with families, physicians, scientists, and pharmaceutical innovators.

The SYNGAP1 Foundation is dedicated to improving the lives of families affected by SYNGAP1 and related overlapping neurological disorders through advocacy, education, and research initiatives.

Sail To Prevail is a non-profit organization that provides therapeutic sailing opportunities for disabled children and adults, helping them overcome adversity and improve their lives.