Hypoglossia-hypodactyly syndrome

Hypoglossia-hypodactyly syndrome is a rare condition that primarily affects the head, face, and limbs. People with this condition are typically born with a short or underdeveloped tongue, missing or incompletely formed fingers and/or toes, and abnormalities in the arms and legs. In many cases, the jaw is also very small, which can affect oral function and appearance. The severity of these physical differences can vary widely among individuals. Some may have several of the features, while others may have only a few. The condition is also known by several other names, including Hanhart syndrome and aglossia-adactylia syndrome. Overall, the information available emphasizes the range of physical characteristics present in this syndrome.

Common signs in people with this condition include an underdeveloped or short tongue, small jaw, and missing or partially absent digits (fingers or toes). There may also be abnormalities in the arms and legs, with the extent of these differences varying from person to person.

The cause of Hypoglossia-hypodactyly syndrome is not fully understood. Currently, there is no clear genetic link or specific risk factor identified from the available information.

Treatment for this syndrome depends on the signs and symptoms present in each person. Management is often tailored to address the specific physical differences and any complications that might arise, with a focus on supportive care.

Information about prognosis is currently limited for this condition. The quality of life for people with this syndrome can vary, depending on the severity of the features and any associated health issues.

Information about current research is currently limited for this condition. Ongoing studies may provide further insights into the underlying causes, natural history, and potential management options in the future.