Doyne honeycomb retinal dystrophy

Doyne honeycomb retinal dystrophy (DHRD) is a condition that affects the eyes and leads to vision loss. It is characterized by the presence of small, round, white spots known as drusen that build up under the retinal pigment epithelium. Over time, these drusen may enlarge and merge, forming a honeycomb pattern in the retina. This condition usually begins in early to mid adulthood, but the age of onset can vary from person to person. The degree of vision loss also differs among people with this condition. DHRD is one of several eye conditions in which structural changes in the retina lead to visual difficulties and varying levels of impairment.

People with Doyne honeycomb retinal dystrophy can experience vision loss as a result of the changes occurring in the eye. The characteristic sign is the appearance of small white spots (drusen) which may later merge. Information about other specific symptoms is currently limited for this condition.

This condition is caused by mutations in the EFEMP1 gene. It follows an autosomal dominant inheritance pattern, which means that a change in just one copy of this gene can lead to the disorder. Genetic factors play a key role, although other risk factors have not been detailed in the available information.

Information about treatment is currently limited for this condition.

The outlook for people with Doyne honeycomb retinal dystrophy can vary greatly, mainly because the degree of vision loss differs among individuals. Information about long-term prognosis is currently limited for this condition.

Information about research is currently limited for this condition.