Congenital herpes virus infection is a group of anomalies that an infant may present as a result of maternal infection and subsequent fetal infection with herpes virus. This virus causes recurrent cut...
Comprehensive, easy-to-understand information about this condition
How we create this content →Documentation on congenital herpes simplex virus infection is limited due to its rarity and the complexities involved in studying its effects. As the condition affects fewer than a specific number of individuals worldwide, systematic clinical studies have been scarce. Additionally, the lack of identified genes and inheritance patterns complicates the understanding of this condition, leading to challenges in clinical characterization.
Infants with congenital herpes simplex virus infection may present with several clinical features. The most common include intrauterine growth retardation and premature birth, both affecting 30-79% of cases. Other notable features include microcephaly and hydranencephaly, which occur in 5-29% of affected infants. These manifestations highlight the severe impact of maternal herpes simplex virus infection on fetal development.
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Currently, there is ongoing research into treatments for congenital herpes simplex virus infection. One notable orphan drug in development is an HSV-1-erasing lentivirus-like particle designed to deliver gRNA-expressing cassette and SpCas9 mRNA. Additionally, there are five active clinical trials exploring various aspects of this condition. For more details on these trials, you can visit ClinicalTrials.gov and search for 'congenital herpes simplex virus infection'.
Actionable guidance for navigating care for congenital herpes simplex virus infection
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Documentation on congenital herpes simplex virus infection is limited due to its rarity and the complexities involved in studying its effects. As the condition affects fewer than a specific number of individuals worldwide, systematic clinical studies have been scarce. Additionally, the lack of identified genes and inheritance patterns complicates the understanding of this condition, leading to challenges in clinical characterization.
Infants with congenital herpes simplex virus infection may present with several clinical features. The most common include intrauterine growth retardation and premature birth, both affecting 30-79% of cases. Other notable features include microcephaly and hydranencephaly, which occur in 5-29% of affected infants. These manifestations highlight the severe impact of maternal herpes simplex virus infection on fetal development.
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Currently, there is ongoing research into treatments for congenital herpes simplex virus infection. One notable orphan drug in development is an HSV-1-erasing lentivirus-like particle designed to deliver gRNA-expressing cassette and SpCas9 mRNA. Additionally, there are five active clinical trials exploring various aspects of this condition. For more details on these trials, you can visit ClinicalTrials.gov and search for 'congenital herpes simplex virus infection'.
Actionable guidance for navigating care for congenital herpes simplex virus infection
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Documentation on congenital herpes simplex virus infection is limited due to its rarity and the complexities involved in studying its effects. As the condition affects fewer than a specific number of individuals worldwide, systematic clinical studies have been scarce. Additionally, the lack of identified genes and inheritance patterns complicates the understanding of this condition, leading to challenges in clinical characterization.
Infants with congenital herpes simplex virus infection may present with several clinical features. The most common include intrauterine growth retardation and premature birth, both affecting 30-79% of cases. Other notable features include microcephaly and hydranencephaly, which occur in 5-29% of affected infants. These manifestations highlight the severe impact of maternal herpes simplex virus infection on fetal development.
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Currently, there is ongoing research into treatments for congenital herpes simplex virus infection. One notable orphan drug in development is an HSV-1-erasing lentivirus-like particle designed to deliver gRNA-expressing cassette and SpCas9 mRNA. Additionally, there are five active clinical trials exploring various aspects of this condition. For more details on these trials, you can visit ClinicalTrials.gov and search for 'congenital herpes simplex virus infection'.
Actionable guidance for navigating care for congenital herpes simplex virus infection
To navigate congenital herpes simplex virus infection, consider seeking a pediatric infectious disease specialist who has experience with viral infections in neonates. While there are currently no specific patient organizations identified for this condition, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov for additional support. Participating in clinical trials may also provide access to cutting-edge treatments and contribute to the understanding of this condition.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.
Organizations with orphan designations or approved therapies for this disease