Corticobasal syndrome (CBS) is a rare neurodegenerative disease characterized by multifaceted motor system dysfunctions and cognitive defects such as asymmetric rigidity, bradykinesia, limb apraxia, a...
Comprehensive, easy-to-understand information about this condition
How we create this content →The limited documentation surrounding corticobasal syndrome is primarily due to its rarity and the lack of systematic clinical studies. As CBS affects a small number of individuals, comprehensive research and characterization of its clinical features have been challenging. This can lead to feelings of isolation for patients and families, but ongoing research efforts may provide more insights in the future.
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Currently, there is one orphan drug designated for corticobasal syndrome: Fasudil hydrochloride, which is still in development. Additionally, there are 28 active clinical trials exploring various aspects of CBS. Patients may find opportunities to participate in these trials, which can be searched at ClinicalTrials.gov using the following link: https://clinicaltrials.gov/search?cond=corticobasal%20syndrome. This research represents a hopeful avenue for advancing our understanding and treatment of CBS.
Actionable guidance for navigating care for corticobasal syndrome
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding corticobasal syndrome is primarily due to its rarity and the lack of systematic clinical studies. As CBS affects a small number of individuals, comprehensive research and characterization of its clinical features have been challenging. This can lead to feelings of isolation for patients and families, but ongoing research efforts may provide more insights in the future.
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Currently, there is one orphan drug designated for corticobasal syndrome: Fasudil hydrochloride, which is still in development. Additionally, there are 28 active clinical trials exploring various aspects of CBS. Patients may find opportunities to participate in these trials, which can be searched at ClinicalTrials.gov using the following link: https://clinicaltrials.gov/search?cond=corticobasal%20syndrome. This research represents a hopeful avenue for advancing our understanding and treatment of CBS.
Actionable guidance for navigating care for corticobasal syndrome
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding corticobasal syndrome is primarily due to its rarity and the lack of systematic clinical studies. As CBS affects a small number of individuals, comprehensive research and characterization of its clinical features have been challenging. This can lead to feelings of isolation for patients and families, but ongoing research efforts may provide more insights in the future.
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Currently, there is one orphan drug designated for corticobasal syndrome: Fasudil hydrochloride, which is still in development. Additionally, there are 28 active clinical trials exploring various aspects of CBS. Patients may find opportunities to participate in these trials, which can be searched at ClinicalTrials.gov using the following link: https://clinicaltrials.gov/search?cond=corticobasal%20syndrome. This research represents a hopeful avenue for advancing our understanding and treatment of CBS.
Actionable guidance for navigating care for corticobasal syndrome
To navigate your journey with corticobasal syndrome, seek a neurologist with expertise in neurodegenerative disorders, particularly those familiar with atypical parkinsonian syndromes. While there are currently no specific patient organizations for CBS, you can access resources from the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Additionally, consider participating in clinical trials, which may provide access to new therapies and contribute to research. Genetic counseling may also be beneficial to discuss any potential risks for family members.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.
Organizations with orphan designations or approved therapies for this disease