prune belly syndrome

Prune belly syndrome is a rare congenital disorder. It is part of a group of conditions known as fetal lower urinary tract obstructions. The condition involves variable dilation of the lower urinary tract, which is the part of the body that helps carry urine out, along with a partial or complete absence of the muscles on the sides and bottom of the abdomen. In addition, many affected individuals, particularly males, experience undescended testes that cannot be felt through physical examination. This combination of urinary tract issues and abnormalities in the abdominal muscles defines the condition and is key to its diagnosis.

People with prune belly syndrome commonly present with problems related to their urinary tract, such as dilation or blockage, as well as weakness or absence of the abdominal muscles. Males with the condition often have non-palpable undescended testes.

Prune belly syndrome is a congenital disorder, meaning it is present at birth. There is evidence that genetics may play a role, with the CHRM3 gene being noted as a known gene associated with the condition. However, the exact causes and all genetic factors are not yet fully understood.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.