Bartter disease type 1

Bartter disease type 1 is a rare genetic condition that affects kidney function. It is known by several names including Bartter syndrome, furosemide type, and hyperprostaglandin E syndrome, among others. The condition is associated with alterations in how the kidneys handle salt, which can lead to imbalances in the body. Due to the limited detailed definition available from current sources, further specifics about the overall nature of the disorder are not fully elucidated in widely available literature. People with this condition may experience complications related to abnormal salt and water balance, though detailed descriptions of the disorder are not provided in the source fields.

Information about symptoms is currently limited for this condition.

Bartter disease type 1 is caused by mutations in the SLC12A1 gene. These genetic changes can affect how the kidneys reabsorb salt, which in turn may lead to electrolyte imbalances. Detailed descriptions of other potential risk factors are not provided in the sources.

Information about treatment options and management approaches is currently limited for this condition.

Information about the outlook and quality of life for people with this condition is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.