Charcot-Marie-Tooth disease type 4

Charcot-Marie-Tooth disease type 4 (CMT4) is a form of peripheral sensorimotor polyneuropathy. This means that the nerves in the arms and legs, which help control movement and sensation, are affected. CMT4 is part of a larger group of Charcot-Marie-Tooth diseases that vary widely in their genetic causes and clinical presentation. The condition is described as genetically heterogeneous, which signifies that various genetic changes can lead to a similar clinical picture. This diversity means that the specific details about how the disease develops can differ from one family to another.

Information about symptoms is currently limited for this condition.

Charcot-Marie-Tooth disease type 4 is considered a genetic condition. It is sometimes referred to by names such as AR-CMT1 and autosomal recessive demyelinating Charcot-Marie-Tooth, which indicate that the condition is passed down in an autosomal recessive manner. The term ‘genetically heterogeneous’ used in its definition shows that different genetic changes can be involved in causing the condition. However, specific details regarding the exact genetic causes are limited.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.