Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with t...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
The documentation surrounding severe pre-eclampsia is limited due to its complex nature and the challenges in systematically studying conditions that affect fewer than 5% of pregnancies. Additionally, the genetic basis has not been established, making it difficult to characterize the condition fully. This lack of comprehensive data can lead to feelings of isolation, but ongoing research is aimed at better understanding and managing this serious condition.
To navigate severe pre-eclampsia effectively, consider seeking a maternal-fetal medicine specialist who has expertise in high-risk pregnancies. Engaging with a genetic counselor may also be beneficial to discuss any potential hereditary implications, even though a genetic basis is not yet identified. For additional resources, you can visit the Genetic and Rare Diseases Information Center at rarediseases.info.nih.gov for information on ongoing studies and support. Participating in clinical trials may provide access to cutting-edge treatments and contribute to research efforts.
There are currently four orphan drugs designated for severe pre-eclampsia, including allogeneic ex-vivo expanded placental adherent stromal cells, digoxin immune fab (ovine), recombinant human placental growth factor, and S-nitrosoglutathione. Additionally, there are 22 active clinical trials investigating various aspects of this condition. For more information on these trials, you can visit ClinicalTrials.gov and search for severe pre-eclampsia.
Actionable guidance for navigating care for severe pre-eclampsia
To navigate severe pre-eclampsia effectively, consider seeking a maternal-fetal medicine specialist who has expertise in high-risk pregnancies. Engaging with a genetic counselor may also be beneficial to discuss any potential hereditary implications, even though a genetic basis is not yet identified. For additional resources, you can visit the Genetic and Rare Diseases Information Center at rarediseases.info.nih.gov for information on ongoing studies and support. Participating in clinical trials may provide access to cutting-edge treatments and contribute to research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.
Organizations with orphan designations or approved therapies for this disease